Some ways to initialise an empty orxVECTOR.

  orxVECTOR position = {};

  orxVECTOR position = {0, 0, 0};

  orxVECTOR position = orxVECTOR_0;

  orxVECTOR position;
  position.fX = 0;
  position.fY = 0;
  position.fZ = 0;
  
  orxVECTOR position;
  orxVector_Set(&position, orx2F(0.0f), orx2F(0), orxFLOAT_0);
  

Uninitialised orxVECTORs can create unintended consequences in your game.

You can also do:

orxVECTOR tilePos;
orxVector_Set(&tilePos, orx2F(80.0f) * x, orx2F(160.0f), orxFLOAT_0);
orxObject_SetPosition(tile, &tilePos);

orxVECTOR pos;
orxObject_GetPosition(player, &pos);
pos.fX = -pos.fX;
orxObject_SetPosition(player, &pos);